The Primary Causes of Parkinson’s Disease

Parkinson's Disease pic

Parkinson’s Disease
Image: WebMD.com

Mitchell Blutt is the founder and CEO of healthcare investment firm Consonance Capital as well as a clinical assistant professor of medicine at Weill Cornell Medical College in New York. A professional scientist and businessman for almost 30 years, Mitchell Blutt has served on numerous boards in support of a variety of organizations, including the Michael J. Fox Foundation for Parkinson’s Research.

The foundation was established by actor Michael J. Fox in 2000 to fund the search for a cure to the disease that affects Fox and as many as 10 million others worldwide. Parkinson’s Disease is a degenerative neurological disorder for which there is currently no known test or biomarker. Research has, however, uncovered evidence of two primary causes of the chronic disease.

In rare cases, Parkinson’s appears to be the result of a genetic mutation involving a single gene, known as the LRRK2 gene. The mutated gene may be passed down through generations, which could explain why there are sometimes multiple cases of the disease within a single bloodline.

Environmental issues have also been known to trigger the development of Parkinson’s. In the case of most patients, both genetic and environmental factors appear to contribute to the onset of Parkinson’s disease.

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